"Polycystic kidney disease" threatened to require her to undergo dialysis at the age of 24! Guangtian Hospital and National Health Research Institutes of Taiwan collaborate on "genetic testing" to aid diagnosis
The hereditary rate of parents suffering from polycystic kidney disease reaches 50%, and children may suffer from kidney dialysis at a young age
Having kidney dialysis at a young age, could it be due to genetics? Ms. Huang, a 24-year-old woman from Taichung, whose father suffered from “autologous dominant polycystic kidney disease” and long-term kidney dialysis, died of the disease many years ago. Polycystic kidney disease is a hereditary disease. Ms. Huang’s examination also revealed that she has stage 3 polycystic kidney disease, and she may need kidney dialysis at a young age.
Wang Jialiang, director of the Department of Nephrology at Guangtian General Hospital, said that polycystic kidney disease has not been well treated in the past. Now new oral drugs can be given to significantly delay the time of dialysis. In addition, the introduction of genetic testing in conjunction with the National Health Research Institutes of Taiwan can help patients with chronic kidney disease to be diagnosed early. treat.
Dr. Wang Jialiang pointed out that polycystic kidney disease is a hereditary disease. As long as one parent has the disease, the chance of his or her children developing the disease is 50%. Patients with polycystic kidney disease may have cysts in their kidneys when they are born, but there are no obvious symptoms in the early stages and are difficult to detect. Generally, after the age of 30 to 40 years old, the gradual deterioration of kidney function will cause high blood pressure, back pain, lumbago, urinary tract stones, and hematuria. , urinary tract infection and other symptoms, but it is too late to confirm the disease.
Early detection of polycystic kidney disease without special symptoms can delay dialysis treatment for up to 7 years
Dr. Wang Jialiang said that polycystic kidney disease has not been well treated in the past. Now, if the disease meets the specific course of polycystic kidney disease, the National Health Insurance Department can provide patients with oral medications, which can inhibit the growth of kidney blisters and delay the deterioration of kidney function by about 30%. , and the earlier it is taken, the more helpful it will be in maintaining the patient’s renal function.
Dr. Wang Jialiang pointed out that chronic kidney disease is divided into stages 1 to 5. When entering stage 5, kidney dialysis is required. According to research, patients who continue to take drugs starting from stage 2 can delay kidney dialysis for 7 years; stage 3 The first stage of kidney dialysis can be postponed for 4 years; the fourth stage can be postponed for about 1 year.
Take Ms. Huang, a 24-year-old polycystic kidney disease patient, as an example. Her kidney function has deteriorated to stage 3. Fortunately, she continues to take medication to maintain her kidney function. I am also glad that the disease was not discovered too late and I was able to receive oral medication as early as possible to slow down the progression of chronic kidney disease.
How to distinguish renal cysts from polycystic kidney disease? Genetic testing helps diagnose disease
Since family history is an important risk factor for polycystic kidney disease, Guangtian General Hospital has collaborated with Dr. Huang Daoyang of the National Health Research Institutes of Taiwan on the “Autologous Dominant Polycystic Kidney Gene Test” to allow patients with a family history of kidney disease to find out whether they have autologous polycystic kidney disease. Dominant polycystic kidney disease gene variant. Huang Daoyang said that kidney cysts are quite common and sometimes difficult to distinguish from autologous dominant polycystic kidney disease. Genetic testing can help with disease diagnosis and eugenics consultation. Patients should drink more water, eat less salt, take blood pressure-lowering drugs, and regularly Physician evaluates treatment.
Zhang Jiazhu, deputy director and nephrologist at Guangtian General Hospital, called on polycystic kidney disease to have no special symptoms in the early stages and can easily be ignored. If your parents or relatives are polycystic kidney disease patients, it is recommended that the public go to the nephrology department for examination, use renal ultrasound, blood drawing, urine testing, and genetic testing to evaluate, and continue to track the status and function of the kidneys. Early detection and early treatment can slow down the deterioration of kidney function.
