Lin Meixiu revealed that she suffers from "acquired hemophilia"! Doctor's reminder: If anemia and bruises are not cured, seek medical attention immediately

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Lin Meixiu revealed that she suffers from "acquired hemophilia"! Doctor's reminder: If anemia and bruises are not cured, seek medical attention immediately

Lin Meixiu was shocked to be diagnosed with “acquired hemophilia”! Anemia and bruises all over the body are warning signs?

Recently, the well-known artist Lin Meixiu was not as good as expected due to the preparation of a new album. She was even diagnosed with “Acquired hemophilia”. The hemoglobin once dropped to 2 g/dl, which is far lower than the normal value of 12 g/dl. dl; In addition, he revealed that he had received “Slim Pen” (incretin-like injection) treatment, which attracted the attention of all walks of life to this incident.

Dr. Chen Shuhui, director of the Hemophilia Center of Taiwan Ministry of Health and Welfare Shuang Ho Hospital, said in an exclusive interview with “healthorn” that acquired hemophilia is caused by the body’s production of antibodies against “coagulation factors”, which in turn induces an immune response and leads to abnormal coagulation function in the body. disease. The most common is the production of antibodies against “factor VIII”.

Dr. Chen Shuhui explained that patients with this disease are prone to symptoms such as large areas of skin bruising and muscle bleeding. Excessive bleeding may cause “anemia”, leading to weakness, dizziness, and poor mobility. When interviewed, Lin Meixiu also said that in the past, she was prone to blood bruising in her legs due to dancing and exercise. Unexpectedly, the blood bruising and swelling in her feet had not healed for a long time. After seeking medical treatment, she underwent a systemic examination and found out that it was acquired blood stasis. Friendly disease.

Half of acquired hemophilia has unknown causes? The fatality rate can reach up to more than 20%?

Is Lin Meixiu’s weight loss through the “Slimming Pen” an indirect cause of acquired hemophilia? Dr. Chen Shuhui clarified that about half of the patients with acquired hemophilia have no known cause; the rest are mostly related to autoimmune diseases (such as rheumatoid arthritis, lupus erythematosus, etc.), blood diseases, cancer, pregnancy and childbirth (young postpartum women) is related. Except for postpartum women, the age of onset is 60-80 years old. It is not necessarily directly related to slimming pen treatment or weight fluctuations, and the public should avoid over-association.

However, Dr. Chen Shuhui emphasized that untreated acquired hemophilia still carries a certain risk of death, with a single bleeding fatality rate of about 3.3%; the death risk related to acquired hemophilia is about 10-22%. In addition, acquired hemophilia will cause severe bleeding in 70% of patients; if the bleeding event occurs in the gastrointestinal tract (bloody stools) or brain, it may be life-threatening, and patients must be vigilant.

What are the treatment guidelines for acquired hemophilia? Patients should avoid “3 things” in their daily lives

What are the current treatment guidelines for acquired hemophilia? Dr. Chen Shuhui explained that treatment is divided into two major goals: one is to “eliminate antibodies” so that it can be cured once and for all; the other is to control bleeding. In terms of eliminating antibodies, the two major therapeutic drugs, “steroids” and the chemotherapy drug “Cyclophosphamide” (drug name: Endoxan), are available in injections and oral drugs. Generally speaking, oral drugs are more convenient; both are also available. Can be used together to have good therapeutic effect. In addition, the target drug Rituximab (drug name Mabthera) is an anti-CD20 monoclonal antibody, and its mechanism is to promote the lysis of B lymphocytes. thereby reducing the production of antibodies.

If the bleeding is severe, two bypass treatment drugs can be used: Factor Eight Injection (NovoSeven) or Coagulation Complex (FEIBA, Factor Eight Inhibitor Bypass Agent). Both are helpful to a certain extent in relieving acute and massive bleeding. Dr. Chen Shuhui pointed out that if patients can follow the doctor’s instructions and take medication regularly and follow up regularly, most of their conditions can improve; and only a few patients will experience recurrence.

Finally, Dr. Chen Shuhui reminded that if acquired hemophilia is diagnosed, patients should avoid collision-related sports, and those taking anticoagulant drugs should also adjust their dosage under the supervision of a physician. In addition, avoid eating foods that can easily cause bleeding in the body. If you find bruises or bleeding symptoms that have not healed for weeks or even months, you should seek medical attention as soon as possible to prevent the condition from worsening and affecting your life.


Further reading:

Can people with hemophilia exercise? Worried about intra-articular bleeding? Doctor: Early administration of coagulation factors is key

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