Fight against the dawn of "long-term COVID-19"? Taiwan research reveals: Omega-3 fatty acids play "8 positive effects"
Does COVID-19 affect the human nervous and mental systems? Doctors reveal 4 potential causes
With the popularization of vaccines, the enhancement of overall immunity, and the follow-up of drug treatment, although the global epidemic, mainly Omicron, is increasingly under control, there are still many patients with the phenomenon of “Long Covid” (Long Covid). Dr. Su Guanbin, deputy director of Annan Hospital, pointed out that even if there are no “organic” sequelae of COVID-19 infection, many recovered patients still suffer from long-term sequelae such as fatigue, anxiety, depression, and body pain.
“Just after the second and third doses of the vaccine, many recipients experienced recurrence of chronic pain, headaches, nerve, bone, joint injuries and other problems, prolonging the symptoms of inflammatory reactions for weeks to months.”
In addition, Dr. Yang Junbai, director of the Department of Neurology at Guangtian Hospital, also stated that the mechanism of neurological complications caused by COVID-19 may be caused by a combination of factors, including long-term tissue damage to the central nervous system due to infection; persistent systemic Inflammation and oxidative stress; poor regulation of the renin-angiotensin-aldosterone system and coagulation system, as well as immune disorders, neurotransmitter and hypothalamic-pituitary-adrenal axis dysfunction; and even the psychosocial stress caused by COVID-19. has a significant impact.
A new dawn against COVID-19! Taiwan research reveals: “Omega-3” plays 8 positive effects
Nowadays, the safety of nutritional medicine is gradually widely accepted, and with the continuous accumulation of scientific evidence, it also has a place in the intervention and prevention of neurological fields. For example, fish oil (Omega-3 polyunsaturated fatty acids) may have a mechanism-regulating effect on the immune system, inflammation, oxidative stress, and psychoneuroimmunity at different stages of COVID-19 infection; it also has anticoagulant and balance contractile hormones in blood vessels. Invertase, resistance to virus invasion and other potential effects.
Recently, Dr. Su Guanbin, Dr. Yang Junbai, and Dr. Zhang Qingmao, director of the Department of Integrative Medicine, Department of Traditional Medicine, Taipei Veterans General Hospital, jointly published “Long-term Symptoms of COVID-19 and Long-Chain Fatty Acids: The Role of Omega-3 Long-Chain Fatty Acids in the Delayed Sequelae of COVID-19” Psychoneuroimmune Effects" paper explores the impact of Omega-3 on immunity, inflammation, oxidative stress and psychoneuroimmunity at different stages of COVID-19 infection.
Research results have found that Omega-3 improves mood and neurocognitive disorders by reducing pro-inflammatory cytokines, changing the hypothalamic-pituitary-adrenal axis, and regulating neuronal substance transmission. In addition, Omega-3 and its metabolites, such as proresolvin mediators (SPMs), have been proven to have immunomodulatory functions and can accelerate the process of clearing chronic inflammation and restoring tissue stability, providing a new therapeutic prospect for COVID-19 symptoms.
Omega-3’s anti-inflammatory effects are confirmed by doctors: providing a new direction for patients with sequelae
Dr. Su Guanbin said that the paper obtained data from animal studies, human clinical trials and epidemiological studies to explain how Omega-3 fights the sequelae of COVID-19 and the role it plays in neurological and psychiatric complications.
Dr. Yang Junbai also explained that Omega-3 and its bioactive metabolites, in addition to interacting with phospholipid metabolism and converting phospholipids into anti-inflammatory metabolites to protect and repair the brain, can also improve oxidative stress, immune disorders, renal Adaptive disorders of the hormone-angiotensin-aldosterone system and coagulation function, as well as psychosocial stress caused by changes in health, social life, and finances.
Although Omega-3 has the above potential effects, the research results still need to be tested and verified by more epidemiological, experimental and clinical randomized trials. However, Dr. Su Guanbin emphasized that the information presented in this retrospective article can be used as a new direction to explore the prevention and effectiveness of Omega-3 on the symptoms of COVID-19, and to provide a new direction for the treatment and prevention of patients diagnosed with COVID-19.
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